Quantum Limits of Knowledge 2021 Tuesday 30th March, 2021 We argue that in canonical quantum gravity there is no fundamental Born rule at the level of the Wheeler-DeWitt equation, and that an effective Born rule emerges only in the Schrödinger approximation for quantum systems on a classical spacetime background. Furthermore, we show that small quantum-gravitational corrections to the Schrödinger equation can render the Born rule unstable. These results are shown to arise naturally in the de Broglie-Bohm pilot-wave formulation of canonical quantum gravity.